{"id":36013,"date":"2020-03-14T02:20:04","date_gmt":"2020-03-14T02:20:04","guid":{"rendered":"https:\/\/one.sightlinemg.com\/navytimes\/uncategorized\/2020\/03\/14\/explainer-how-do-you-test-for-coronavirus\/"},"modified":"2026-08-08T19:36:45","modified_gmt":"2026-08-08T19:36:45","slug":"explainer-how-do-you-test-for-coronavirus","status":"publish","type":"post","link":"https:\/\/one.sightlinemg.com\/navytimes\/news\/your-navy\/2020\/03\/14\/explainer-how-do-you-test-for-coronavirus\/","title":{"rendered":"Explainer: How do you test for coronavirus?"},"content":{"rendered":"\n

Navy Times editor\u2019s note: <\/b>In several of our stories, we\u2019ve trotted out the Navy phrase \u201cpresumptive positive<\/a>\u201d to indicate a sailor who has been tested<\/a> and is believed to have been infected with the novel strain of coronavirus. As we\u2019ve explained it, this means that a patient was tested by a clinic \u2014usually a state or community health agency \u2014 using a kit. The \u201cpresumptive\u201d label isn\u2019t removed until the results are confirmed by the Centers for Disease Control and Prevention, even if everyone knows the sailor has been infected with COVID-19. Dr. Maureen Ferran<\/a> explains why this is so.<\/p>\n\n\n\n

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A health worker carries a biohazard bag at the drive-through coronavirus testing site that opened on Friday by UCHealth in Colorado Springs, Colo. (Chancey Bush\/The Gazette via AP)<\/figcaption><\/figure>\n\n\n\n

Who gets tested for the virus?<\/b><\/i><\/p>\n\n\n\n

Currently there are two main reasons someone would be tested for the coronavirus: having symptoms or exposure to an infected person.<\/p>\n\n\n\n

The main symptoms of COVID-19, the disease caused by the coronavirus SARS-CoV-2, are fever, dry cough and shortness of breath<\/a>. These look a lot like the flu and the common cold, so it takes a physician to determine if testing for the virus is necessary.<\/p>\n\n\n\n

Initially, the Centers for Disease Control and Prevention recommended testing only people with symptoms and who had potentially been exposed to the virus. But to the surprise of public health officials, several of the first people in the U.S. who tested positive for the virus had no obvious exposure. <\/p>\n\n\n\n

This development suggested that the virus was being transmitted locally, meaning it was spreading from person to person easily and\/or that people may have been transmitting the virus without experiencing serious symptoms.<\/p>\n\n\n\n

In response, on March 4 the CDC changed its recommendations to allow anyone with COVID-19-like symptoms to be tested<\/a> as long as a doctor approved the request. Since the number of available tests is limited, the CDC is encouraging physicians to minimize unnecessary testing and consider a patient\u2019s exposure risks<\/a> before ordering tests.<\/p>\n\n\n\n

As of writing this, there are no specific treatments available for COVID-19, but that does not mean testing is pointless. <\/p>\n\n\n\n

Perhaps most importantly, testing is done so that infected patients can be quarantined and the spread of the virus slowed. Another benefit of testing is that it lets public health workers build a more accurate picture of the number of cases<\/a> and how the virus is spreading in the population.<\/p>\n\n\n\n

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Medical personnel discuss patients that had been admitted for testing for the coronavirus at the entrance Central Maine Medical Center on Friday in Lewiston, Maine. (Robert F. Bukaty\/AP)<\/figcaption><\/figure>\n\n\n\n

What it is like to get tested?<\/b><\/i><\/p>\n\n\n\n

For a patient, the process of being tested for the virus is easy and can potentially be done almost anywhere<\/a>. It typically involves taking a swab from deep in a patient\u2019s nasal cavity to collect cells from the back of the nose<\/a>.<\/p>\n\n\n\n

The sample is then sent to a lab, where it will be tested to determine if the patient\u2019s cells are infected with the virus. <\/p>\n\n\n\n

The same process is used to collect a sample from a patient who is tested for flu<\/a>.<\/p>\n\n\n\n

How does the test work?<\/b><\/i><\/p>\n\n\n\n

While collecting a sample is easy, actually determining whether a person is infected with the coronavirus is much more complicated. The current method looks for the virus\u2019s genetic material (RNA) in a patient\u2019s cells.<\/p>\n\n\n\n

In order to detect the presence of RNA in the patient\u2019s sample, labs perform a test called reverse-transcription polymerase chain reaction<\/a>. This method first converts any viral RNA to DNA. Then the DNA is replicated millions of times until there are enough copies to detect using a specialized piece of equipment called a quantitative PCR instrument.<\/p>\n\n\n\n

If genetic material from the virus is found in the sample, then the patient is infected with the virus.<\/p>\n\n\n\n

It takes 24-72 hours to get the results of a test<\/a>. During the early ramp-up of testing, there were some concerns about the test\u2019s accuracy<\/a> after one study found 3 percent of tests in China came back negative when the samples were actually positive. <\/p>\n\n\n\n

But this type of genetic test is generally very accurate \u2013 more so even than rapid flu tests<\/a> \u2013 and the benefits of testing outweigh the risk of an error.<\/p>\n\n\n\n

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National Guard troops wait for patients to arrive for COVID-19 coronavirus testing on Friday in New Rochelle, N.Y. State officials have set up a \u201ccontainment area\u201d in the New York City suburb, where schools and houses of worship are closed within a 1-mile radius of a point near a synagogue where an infected person with coronavirus had attended events. (John Minchillo\/AP)<\/figcaption><\/figure>\n\n\n\n

Does the US have enough tests?<\/b><\/i><\/p>\n\n\n\n

The availability of tests has been a big issue. <\/p>\n\n\n\n

Prior to Feb. 29, the CDC was the only place approved by the FDA to develop, produce and process tests<\/a>. However, as the number of suspected cases climbed and doctors approved more people for testing, demand to be tested soared.<\/p>\n\n\n\n

The test for the coronavirus requires a kit, specialized equipment and specially trained personnel<\/a>. Faulty and slow development of test kits and the initial requirement that all tests be processed at the CDC contributed to the slow rollout across the U.S<\/a>.<\/p>\n\n\n\n

As pressure on the federal government to make tests available increased, the FDA announced a new policy on Feb. 29 that made it easier for commercial and academic laboratories to develop their own tests<\/a> and allowed other certified labs to test patient samples.<\/p>\n\n\n\n

Integrated DNA Technologies, a CDC contractor, shipped 700,000 tests to commercial, academic and health care laboratories on March 6. Quest Diagnostics and LabCorp, two large commercial test manufacturers, started making their own test kits, which became available on March 9<\/a>.<\/p>\n\n\n\n

Many companies, hospitals and other institutions are now racing to develop more tests to diagnose COVID-19<\/a>.<\/p>\n\n\n\n

On March 10, Alex Azar, secretary of Health and Human Services, announced that 2.1 million testing kits are now available and more than 1 million have shipped<\/a> to certified labs for testing. Millions more are expected to<\/a> ship out this week<\/a>.<\/p>\n\n\n\n

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Poles wait for the results of their coronavirus tests at a contagious diseases hospital in Warsaw on Friday. Poland has 64 confirmed cases of COVID-19 infections and one fatality. (Czarek Sokolowski\/AP)<\/figcaption><\/figure>\n\n\n\n

Does everyone really need to be tested?<\/b><\/i><\/p>\n\n\n\n

Realistically, it isn\u2019t feasible to test everyone who is sick in the U.S. <\/p>\n\n\n\n

Therefore, most health officials believe it is important to prioritize the testing of people who need it the most<\/a>: those at high risk such as health care workers who have been in contact with COVID-19 patients; symptomatic people in areas with high infection rates; and people 65 years of age and older with chronic health issues, such as heart disease, lung disease or diabetes. As more tests become available, it will be possible to test more people.<\/p>\n\n\n\n

There\u2019s also a need to develop faster tests that do not require special equipment and personnel. Testing allows experts to better understand how the outbreak is progressing and try to predict the impact the virus will have on society.<\/p>\n\n\n\n

As with all outbreaks, this pandemic will end. In the meantime, however, people need to wash their hands and try to minimize their risk of exposure. <\/p>\n\n\n\n

There is much to be learned about this novel coronavirus. Only time will tell if it disappears from the human population, as SARS did in 2004, or becomes a seasonal disease like flu<\/a>.<\/p>\n\n\n\n

Dr. <\/i>Maureen Ferran<\/i><\/a> is an associate professor of Biology in the Thomas H. Gosnell School of Life Sciences at Rochester Institute of Technology. An expert on how viruses evade a host\u2019s immune response, her Her research lab focuses on the development of viruses as a cancer therapy and the use of imaging agents to detect and target cancer.<\/i><\/p>\n\n\n\t